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宋颂

研究员

宋颂,北京大学药学院,研究员,博士生导师

 

1985年出生,中共党员

 

教育经历

2007年9月-2012年7月: 南开大学元素所,理学博士,导师:周其林教授

2003年9月-2007年7月: 南开大学化学学院,理学学士

 

研究经历

2021年8月-至今:北京大学药学院,新体制助理教授,研究员,博导

2018年1月-2021年7月:北京大学药学院,新体制助理教授,副研究员,博导

2015年8月-2017年12月: 北京大学药学院,助理研究员

2013年8月-2015年7月: 北京大学药学院博士后,合作导师:焦宁教授

2012年7月-2013年7月:南开大学元素所,讲师

 

研究方向

绿色选择性亲电反应,包括卤化、烷基化、硫化反应

 

承担科研项目

2024-2027,醇的催化脱羟基官能团化反应研究,基金委面上项目,项目负责人

2018-2022,手性路易斯碱催化的卤化反应研究,基金委面上项目,项目负责人

2021-2024,协同催化缺电子芳烃的亲电官能团化反应研究,基金委面上项目,项目负责人

2020-2022,生脉散类名优中成药为范例的中药作用机制解析创新方法研究,国家重点研发计划,子课题负责人

2022-2024,靶向清道夫受体(SR-A)的类风湿关节炎小分子抑制剂药物研发,北京市科技新星交叉项目,项目合作方

2020.9-2023.8,生物活性分子的卤化反应修饰技术开发及先导化合物发现,北京市科技新星计划,项目负责人

2017-2019,亚砜促进的卤化反应研究,基金委青年项目,项目负责人

 

奖励与荣誉

教育部“长江学者奖励计划”青年学者(2022)

北京市科技新星,2020年

绿叶生物医药杰出青年学者奖,2020年

北京大学优秀博士后,2015年

 

发表文章

1. Weijin Wang, Xiaoxue Yang, Rongheng Dai, Zixi Yan, Jialiang Wei, Xiaodong Dou, Xu Qiu, Hongliang Zhang, Chen Wang, Yameng Liu, Song Song*, Ning Jiao*, Catalytic Electrophilic Halogenation of Arenes with Electron-Withdrawing Substituents. J. Am. Chem. Soc. 2022, 144 , 13415. (IF: 16)

2. Xinwei Li, Zengrui Cheng, Jianzhong Liu, Ziyao Zhang, Song Song*, Ning Jiao*, Selective desaturation of amides: a direct approach to enamides. Chem. Sci. 2022, 13 , 9056. (IF: 9.9)

3. Weijin Wang, Xinyao Li, Xiaoxue Yang, Lingsheng Ai, Zhiwen Gong, Ning Jiao, Song Song*, Oxoammonium salts are catalysing efficient and selective halogenation of olefins, alkynes and aromatics. Nat. Commun. 2021, 12 , 3873. (IF: 16)

4. Hao Wu, Xinyao Li, Zixi Yan, Nana Ma, Song Song*, Guisheng, Zhang*, Ning Jiao*, Cu(I)-Catalyzed [2 + 2 + 1] Cycloaddition of Amines, Alkynes, and Ketenes: An Umpolung and Regioselective Approach to Full-Substituted β-Pyrrolinones. Org. Lett. 2021, 23 , 762. (IF: 6.2)

5. Song Song,Xinyao Li, Jialiang Wei, Weijin Wang, Yiqun Zhang, Lingsheng Ai, Yuchao Zhu, Xiaomeng Shi, Xiaohui Zhang, Ning Jiao*, DMSO-catalysed late-stage chlorination of (hetero)arenes. Nat. Catal. 2020, 3 , 107. (IF: 40)

6. Xiaojin Wen, Xinyao Li, Xiao Luo, Weijin Wang, Song Song*, Ning Jiao*, Intramolecular Csp3-H/C-C bond amination of alkyl azides for the selective synthesis of cyclic imines and tertiary amines. Chem. Sci. 2020, 11 , 4482. (IF: 9.9)

7. Weijin Wang, Tongyu Huo, Xinyi Zhao, Qixue Qin, Yujie Liang, Song Song*, Guosheng Liu, Ning Jiao*, Nitromethane-Enabled Fluorination of Styrenes and Arenes. CCS Chem. 2020, 2 , 566.

8. Qixue Qin, Weijin Wang, Cheng Zhang, Song Song*, Ning Jiao*, A metal-free desulfurizing radical reductive C–C coupling of thiols and alkenes. Chem. Commun. 2019, 55 , 10583. (IF: 6)

9. Xu Qiu, Xiaoxue Yang, Yiqun Zhang, Song Song*, Ning Jiao, Efficient and practical synthesis of unsymmetrical disulfides via base-catalyzed aerobic oxidative dehydrogenative coupling of thiols. Org. Chem. Front. 2019, 6 , 2220. (IF: 5.5)

10. Jianzhong Liu, Xiaojin Wen, Chong Qin, Xinyao Li, Xiao Luo, Ao Sun, Bencong Zhu, Song Song*, Ning Jiao*, Oxygenation of Simple Olefins through Selective Allylic C-C BondCleavage: A Direct Approach to Cinnamyl Aldehydes. Angew. Chem. Int. Ed. 2017, 56 , 11940. (IF: 16)

11. Song Song*,Yiqun Zhang, Adeli Yeerlan, Bencong Zhu, Jianzhong Liu, Ning Jiao*, Cs2CO3-Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes. Angew. Chem. Int. Ed. 2017, 56 , 2487. (IF: 16)

12. Yuchao Zhu, Xiaojin Wen, Song Song*, Ning Jiao*, Silver-Catalyzed Radical Transformation of Aliphatic Carboxylic Acids to Oxime Ethers. ACS Catal. 2016, 6 , 6465.

13. Song Song,Xinwei Li, Xiang Sun, Yizhi Yuan, Ning Jiao*, Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid. Green Chem. 2015, 17 , 3285.

14. Song Song,Xiaoqiang Huang, Yu-Feng Liang, Conghui Tang, Xinwei Li, Ning Jiao*, From simple organobromides or olefins to highly value-added bromohydrins: a versatile performance of dimethyl sulfoxide. Green Chem. 2015, 17 , 2727.

15. Song Song,Xiang Sun, Yizhi Yuan, Ning Jiao*, Efficient and practical oxidative bromination and iodination of arenes and heteroarenes with DMSO and hydrogen halide: A mild protocol for late-stage functionalization. Org. Lett. 2015, 17 , 2886.

16. Song Song, Shou-Fei Zhu, Shuang Yang, Shen Li, Qi-Lin Zhou*, Enantioselective iridium-catalyzed hydrogenation of β,γ-unsaturated carboxylic acids: An efficient approach to chiral 4-alkyl-4-aryl butanoic acids. Angew. Chem. Int. Ed. 2012, 51 , 2708.

17. Song Song, Shou-Fei Zhu, Yan-Bo Yu, Qi-Lin Zhou*, Carboxy-directed asymmetric hydrogenation of 1,1-diarylethenes and 1,1-dialkylethenes. Angew. Chem. Int. Ed. 2013, 52 , 1556.

18. Song Song, Shou-Fei Zhu, Liu-Yang Pu, Qi-Lin Zhou*, Iridium-catalyzed enantioselective hydrogenation of unsaturated heterocyclic acids. Angew. Chem. Int. Ed. 2013, 52 , 6072.