梁磊
理学博士副教授硕士生导师
电话：+86-10-82801505 邮箱：leiliang@bjmu.edu.cn
学习经历
2000.9-2004.7 四川大学化学学院（理学学士）
2004.9-2007.3 四川大学化学学院（硕博连读）
2007.4-2008.4 美国伊利诺依大学厄巴纳-香槟分校化学学院（联合培养博士）
2008.5-2009.7 四川大学化学学院（理学博士）
工作经历
2009.7-2011.6 北京大学化学与分子工程学院（博士后）
2011.7-2014.7 北京大学药学院讲师
2014.8至今 北京大学药学院副教授，硕士生导师
授课
《药物化学》，本科生《药物化学实验》
研究方向
1. 基于靶点的药物设计、优化及构效关系研究
2. 用于疾病诊断的分子探针的设计及应用
3. 药物分子合成方法学的探索
奖励
1. 2012年北京大学药学院第十二届青年教师教学演示竞赛一等奖
2. 2012年北京大学第十二届青年教师教学演示竞赛二等奖（医科类）
3. 2013年北京大学医学部优秀教师
4. 2013年北京大学医学部优秀党员
科研成果
1. Guanyu Yang, Qi Sun, Chao Wang,Lei Liang,* Fengrong Xu, Yan Niu, Ping Xu,* Design, synthesis and biological evaluation of sulfonamide flavone derivatives as potential 20S proteasome inhibitors. J. Chin. Pharm. Sci. 2014, 23 (9), 626–630;
2. Wei Wang, Lei Liang,* Fengrong Xu, Wenjie Huang, Yan Niu, Qi Sun, Ping Xu,* Ruthenium-Catalyzed Switchable N–H/C–H Alkenylation of 6-Phenyl(dihydro)pyridazinones with Alkynes. Eur. J. Org. Chem. 2014, 6863–6867;
3. Lei Liang, Wei Wang, Jun Wu, Fengrong Xu, Yan Niu, Bo Xu*, Ping Xu*, Rational Design, Green Synthesis, and Initial Evaluation of a Series of Full-Color Tunable Fluorescent Dyes Enabled by the Copper-Catalyzed N-Arylation of 6-Phenyl Pyridazinones and Their Application in Cell Imaging. Chem. Eur. J. 2013, 19, 13774-13782;
4. Lei Liang, Wei Wang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu*, Relay Catalysis by a Multifunctional Cu Catalyst in a Tandem Dehydro-/Dehalogenation Sequence along with N-Arylation. Org. Lett, 2013, 15, 2770-2773;
5. Lei Liang, Guanyu Yang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu*, A Copper-Catalyzed Aerobic Cascade Dehydrogenative Dehalogenative Reaction. Adv. Syn&Cat, 2013, 355, 1284-1290;
6. Lei Liang, Guanyu Yang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu*, Copper-Catalyzed Aerobic Dehydrogenation of C–C to C=C Bonds in the Synthesis of Pyridazinones. Eur. J. Org. Chem. 2013, 6130–6136;
7. Y.-B. Cai, Lei Liang, J. Zhang*, H.-L. Sun, and J.-L. Zhang*, μ-Hydroxyl trinuclear copper(II) clusters: reactivity and unusual formation in the three-component synthesis of 1,2,3-triazoles in aqueous media. Dalton Trans., 2013, 42, 5390-5400;
8. Lei Liang, H. Lv, Y. Yu, P. Wang, J.-L. Zhang *, Iron(III) tetrakis(pentafluorophenyl)porpholactone catalyzes nitrogen atom transfer to C=C and C-H bonds with organic azides. Dalton Trans., 2012, 41, 1457-1460;
9. D. K. Garner, Lei Liang, D. A. Barrios, J.-L. Zhang *, Y. Lu*, The Important Role of Covalent Anchor Positions in Tuning Catalytic Properties of a Rationally Designed MnSalen-Containing Metalloenzyme. ACS Catal., 2011, 1, 1083-1089;
10. Lei Liang, G. Rao, H.-L. Sun, J.-L. Zhang *, Aerobic Oxidation of Primary Alcohols Catalyzed by Copper Salts and Catalytically Active m-Hydroxyl-Bridged Trinuclear Copper Intermediate. Adv. Synth. Catal., 2010, 352, 2371-2377;
11. J.-L. Zhang , D.K. Garner, Lei Liang, D. A. Barrios, Y. Lu*, Chem. Eur. J., 2009, 15, 7481-7489;
12. Lei Liang, Zhengkai Li, Xiangge Zhou, Pyridine N-Oxides as Ligands in Cu-Catalyzed N-Arylation of Imidazoles in Water, Org. Lett., 2009, 11, 3294-3297;
