Personal Information
Name: Song Song Email: ssong@bjmu.edu.cn Tel: (+86)-15711264118
Address:38 Xueyuan Road, School of Pharmaceutical Sciences, Peking University, Haidian District, Beijing100191, China
Education
2007- 2012
|
Ph.D. in Organic Chemistry, Nankai University, Tianjin, China
Advisor: Prof. Qi-Lin Zhou
|
2003- 2007
|
B.Sc. in Chemistry, Nankai University, Tianjin, China
Advisor: Prof. Qi-Lin Zhou
|
Professional Experience
2018-present
|
Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China
|
|
|
2015-2017
|
Research Assistant, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China
|
2013-2015
|
Postdoctoral Fellow, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China
|
Awards and Honors
-
Peking University Excellent Advisor for Undergraduate Thesis (2024)
-
Peking University Medicine Youth Science and Technology Award (2023)
-
Asian Core Program Lectureship Award (2023)
-
Yangtze River Scholar Award Program for Young Scholars(2022)
-
Rising Stars from the Beijing Nova Program (2020)
-
Luye Biomedical Outstanding Young Scholar Award (2020)
-
ExcellentPostdoctoral Fellow of Peking University (2015)
-
Tianjin Excellent Doctoral Thesis (2014)
Research Interests
1. Methodologies on halogenation reactions
2. Methodologies on aromatic functionalization
Grant Funding
Grant period
|
Grant Type
|
Funding Agency
|
Amount
(million RMB)
|
2019-2022
|
National Key Research and
Development Program
(2019YFC1708902), co-PI
|
Ministry of
Science and
Technology
|
0.92
|
2023-2026
|
National Key Research and
Development Program
(2023YFF1205103), co-PI
|
0.68
|
2024-2027
|
General Program of National
Natural Science Fund
(22371007), PI
|
National Natural Science
Foundation of China
|
0.5
|
2021-2024
|
General Program of National
Natural Science Fund
(22071005), PI
|
0.63
|
2019-2022
|
General Program of National Natural Science Fund
(21871011), PI
|
0.65
|
2017-2019
|
Youth Program of National Natural Science Fund
(21602005), PI
|
0.21
|
2018-2023
|
Start-up Fund, PI
|
Peking University
|
1.00
|
2022-2026
|
Yangtze River Scholar Award Program for Young Scholars
|
1.00
|
2020-2022
|
Beijing Nova ProgramZ201100006820099
|
Natural Science Foundation of Beijing
|
0.55
|
2022-2024
|
Beijing Nova Program
Z211100002121163
|
0.15
|
Publications
-
Tieqiao Wang, Chao Li, Jingxuan Mi, Hongye Wang, Lei Chen, Qingxuan Kong1 Ning Jiao, Song Song,* Skeletal Editing of Pyridine and Quinoline N-Oxides through Nitrogen to Carbon Single Atom Swap.CCS Chem.2024, DOI: 10.31635/ccschem.024.202404133
-
Chao Li, Zixi Yan, Bingding Wang, Jiaxing Li, WeipingLyu, Zhixing Wang, Ning Jiao*, Song Song*, Regioselective synthesis of 4-functionalized pyridines. Chem2024, 10, 628.
-
Chao Li, Lei Chen, Hongye Wang, Zixi Yan, Bin Lyu, WeipingLyu, Changwei Jiang, Dehua Lu, Jiaxing Li, Ning Jiao, Song Song*, C—F Bond Insertion into Indoles with CHBr2F: An Efficient Method to Synthesize Fluorinated Quinolines and Quinolones. Chin. J. Chem.2024, 42, 1128.
-
Hongye Wang, Zhaoting Li, Rongheng Dai, Ning Jiao, Song Song*, An efficient and mild oxidative approach from thiols to sulfonyl derivatives with DMSO/HBr. Chem. Sci.2023, 14, 13228.
-
Weijin Wang, Hongye Wang, Rongheng Dai, Yachong Wang, Zhaoting Li, Xiaoxue Yang, Bin Lu, Ning Jiao, Song Song*, Organocatalytic Deoxyhalogenation of Alcohols with Inorganic Halides. ACS Catal. 2023, 13, 9033.
-
Hongliang Zhang, Weijin Wang, Bingding Wang, Hui Tan, Ning Jiao, Song Song*, Electrophilic amidomethylation of areneswithDMSO/MeCN reagents. Org. Chem. Front.2023, 9, 2430.
-
Weijin Wang, Xiaoxue Yang, Rongheng Dai, Zixi Yan, Jialiang Wei, Xiaodong Dou, Xu Qiu, Hongliang Zhang, Chen Wang, Yameng Liu,Song Song*, Ning Jiao*, Catalytic Electrophilic Halogenation of Arenes with Electron-Withdrawing Substituents. J. Am. Chem. Soc.2022, 144, 13415.
-
Xinwei Li, Zengrui Cheng, Jianzhong Liu, Ziyao Zhang, Song Song*, Ning Jiao*, Selective desaturation of amides: a direct approach to enamides. Chem. Sci.2022, 13, 9056.
-
Weijin Wang, Xinyao Li, Xiaoxue Yang, Lingsheng Ai, Zhiwen Gong, Ning Jiao, Song Song*, Oxoammonium salts are catalysing efficient and selective halogenation of olefins, alkynes and aromatics. Nat. Commun.2021, 12, 3873.
-
Hao Wu, Xinyao Li, Zixi Yan, Nana Ma, Song Song*, Guisheng, Zhang*, Ning Jiao*, Cu(I)-Catalyzed [2 + 2 + 1] Cycloaddition of Amines, Alkynes, and Ketenes: An Umpolung and Regioselective Approach to Full-Substituted β-Pyrrolinones. Org. Lett. 2021, 23, 762.
-
Song Song,Xinyao Li, Jialiang Wei, Weijin Wang, Yiqun Zhang, Lingsheng Ai, Yuchao Zhu, Xiaomeng Shi, Xiaohui Zhang, Ning Jiao*, DMSO-catalysed late-stage chlorination of (hetero)arenes. Nat. Catal. 2020, 3, 107.
-
Xiaojin Wen, Xinyao Li, Xiao Luo, Weijin Wang, Song Song*, Ning Jiao*, Intramolecular Csp3-H/C-C bond amination of alkyl azides for the selective synthesis of cyclic imines and tertiary amines. Chem. Sci.2020,11, 4482.
-
Weijin Wang, TongyuHuo, Xinyi Zhao, Qixue Qin, Yujie Liang, Song Song*, Guosheng Liu, Ning Jiao*, Nitromethane-Enabled Fluorination of Styrenes and Arenes. CCS Chem.2020, 2, 566.
-
Qixue Qin, Weijin Wang, Cheng Zhang, Song Song*, Ning Jiao*, A metal-free desulfurizing radical reductive C–C coupling of thiols and alkenes.Chem. Commun. 2019, 55, 10583.
-
Xu Qiu, Xiaoxue Yang, Yiqun Zhang, Song Song*, Ning Jiao, Efficient and practical synthesis of unsymmetrical disulfides via base-catalyzed aerobic oxidative dehydrogenative coupling of thiols. Org. Chem. Front.2019, 6, 2220.
-
Jianzhong Liu, Xiaojin Wen, Chong Qin, Xinyao Li, Xiao Luo, Ao Sun, Bencong Zhu, Song Song*, Ning Jiao*, Oxygenation of Simple Olefins through Selective Allylic C-C BondCleavage: A Direct Approach to Cinnamyl Aldehydes. Angew. Chem. Int. Ed. 2017, 56, 11940.
-
Song Song*,Yiqun Zhang, AdeliYeerlan, Bencong Zhu, Jianzhong Liu, Ning Jiao*, Cs2CO3-Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes.Angew. Chem. Int. Ed. 2017, 56, 2487.
-
Yuchao Zhu, Xiaojin Wen, Song Song*, Ning Jiao*, Silver-Catalyzed Radical Transformation of Aliphatic Carboxylic Acids to Oxime Ethers. ACS Catal.2016, 6, 6465.
-
Zhu Yuchao, Li Xinyao, Wang Xiaoyang, Huang Xiaoqiang, Shen Tao, Zhang Yiqun, Sun Xiang, Zou Miancheng, Song Song*, Ning Jiao*, Silver-Catalyzed Decarboxylative Azidation of Aliphatic Carboxylic Acids. Org. Lett. 2015, 17, 4702.
-
Song Song,Xiang Sun, Yizhi Yuan, Ning Jiao*, Efficient and practical oxidative bromination and iodination of arenes and heteroarenes with DMSO and hydrogen halide: A mild protocol for late-stage functionalization.Org. Lett. 2015, 17, 2886.
-
Song Song,Xinwei Li, Xiang Sun, Yizhi Yuan, Ning Jiao*, Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid. Green Chem.2015, 17, 3285.
-
Song Song,Xiaoqiang Huang, Yu-Feng Liang, Conghui Tang, Xinwei Li, Ning Jiao*, From simple organobromides or olefins to highly value-added bromohydrins: a versatile performance of dimethyl sulfoxide. Green Chem. 2015, 17, 2727.
Prior to PKU
-
Song Song, Shou-Fei Zhu, Shuang Yang, Shen Li, Qi-Lin Zhou*, Enantioselective iridium-catalyzed hydrogenation of β,γ-unsaturated carboxylic acids: An efficient approach to chiral 4-alkyl-4-aryl butanoic acids. Angew. Chem. Int. Ed. 2012, 51, 2708.
-
Song Song, Shou-Fei Zhu, Yan-Bo Yu, Qi-Lin Zhou*, Carboxy-directed asymmetric hydrogenation of 1,1-diarylethenes and 1,1-dialkylethenes. Angew. Chem. Int. Ed. 2013, 52, 1556.
-
Song Song, Shou-Fei Zhu, Liu-Yang Pu, Qi-Lin Zhou*, Iridium-catalyzed enantioselective hydrogenation of unsaturated heterocyclic acids. Angew. Chem. Int. Ed. 2013, 52, 6072.
-
Song Song, Shou-Fei Zhu, Shen Li, Qi-Lin Zhou*, Iridium-Catalyzed Enantioselective Hydrogenation of α,β-Unsaturated Carboxylic Acids with Tetrasubstituted Olefins.Org. Lett. 2013, 14, 3722.
Patents
-
Song Song, Ning Jiao, Weijin Wang. Rongheng Dai. An efficient halogenation synthesis method for alkyl halides. Patent No. ZL202210308725.1
-
Song Song, Ning Jiao, Rongheng Dai. An efficient synthesis method for aryl alkyl thioethers. Patent No.ZL202210444692.3
-
Ning Jiao, Song Song. Low-cost and efficient synthesis of halogenated alcohols and their derivatives. Patent No. ZL201510033063.1
-
Ning Jiao, Yufeng Liang, Song Song. An efficient synthesis method for catechol compounds.Patent No. ZL201610166390.9
-
Ning Jiao, Song Song, Weijin Wang.An efficient synthesis method for aryl halides.Patent No. ZL202011069035.2
-
Ning Jiao, Siwang Yu, Song Song, Yameng Liu, Simin Yang. Phenoxy carboxylic acid compounds and medical uses thereof. Patent No. ZL201910783280.0
-
Ning Jiao,Song Song, Shenan Wang, Jialiang Wei. A synthesis method of fipronil and its analogues. Patent No. ZL 201910510802X
-
Yimin Cui, Xiaocong Pang, Yanlun Gu, Xiaojiao Sun, Bingqi Dong, Song Song, Haitao Liu, Xu He. Indazole hydrazide compound and application thereof. Patent No. WO 2022/170822
Invited Lectures
-
Chiral China 2024 Symposium (2024/7), Kunming
-
The 2nd Slender West Lake Synthetic Chemistry Forum (2024/5), Yangzhou
-
The 16th International Conference on Cutting-Edge Chemistry in Asia (2023/12), Singapore
-
The Chinese National Conference on Synthetic Chemistry (2023/10), Guangzhou
-
Seminar on Frontiers of Synthetic Chemistry (2020/12), Beijing
Mentoring
Time
|
Name
|
Prev. Position
|
Current Position
|
2023-present
|
Qingxuan Kong
|
PhD student
|
|
2022-present
|
Changwei Jiang
|
PhD student
|
|
2022-present
|
Wenshu Hu
|
PhD student
|
|
2021-present
|
Lei Chen
|
PhD student
|
|
2021-present
|
Bin Lu
|
PhD student
|
|
2020-present
|
Chao Li
|
PhD student
|
|
2018-2022
|
Hongliang Zhang
|
PhD student
|
Betta Pharmaceuticals Co., Ltd.
|
2023-present
|
Tieqiao Wang
|
Master student
|
|
2023-present
|
Jingxuan Mi
|
Master student
|
|
2022-present
|
Zhaoting Li
|
Master student
|
|
2022-present
|
Jiaxing Li
|
Master student
|
|
2021-2024
|
Shihan Geng
|
Master student
|
PhD student at Peking University
|
2021-2024
|
Hongye Wang
|
Master student
|
PhD student at Brown University
|
2020-2023
|
Bingding Wang
|
Master student
|
Dynamics Inc. Co.,Ltd.
|
2019-2022
|
LingyuSu
|
Master student
|
PhD student at Peking University
|
2019-2022
|
Rongheng Dai
|
Master student
|
Yunnan Baiyao Group Co., Ltd.
|
2018-2021
|
Zixi Yan
|
Master student
|
PhD student at Emory University
|
2023-present
|
Haoming Qin
|
Bachelor student
|
|
2021-2023
|
Weijin Wang
|
Bachelor student
|
PhD student atécole Polytechnique Fédérale de Lausanne
|
Teaching
Organic Chemistry (Department of MedicinalChemitry)
|
2019-present (~40 undergraduate students), ~36 hours/year
|
Organic Chemistry (Department of Language and Culture in Medicine)
|
2019-present (~40 undergraduate students), ~18 hours/year
|
Organic Chemistry Labs
|
2019-present (~120 undergraduate students), ~40 hours/year
|
Service
-
Member of the Chinese Chemical Society(2015-present)
-
Member of the Chinese Pharmaceutical Association (2023-present)
-
Assoc. Director of the Medicinal Chemistry Department(2023-present)
-
Reviewers for Research Journals(2015-present)
-
Grant Reviewer for National Natural Science Foundation of China (2018-present)