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SONG Song

Tenure-Track Assistant Professor

 

 

 

 

Personal Information
Name: Song Song      Email: ssong@bjmu.edu.cn     Tel: (+86)-15711264118
Address:38 Xueyuan Road, School of Pharmaceutical Sciences, Peking University, Haidian District, Beijing100191, China

 

Education

2007- 2012

Ph.D. in Organic Chemistry, Nankai University, Tianjin, China
Advisor: Prof. Qi-Lin Zhou

2003- 2007

B.Sc. in Chemistry, Nankai University, Tianjin, China
Advisor: Prof. Qi-Lin Zhou

Professional Experience

 

2018-present

Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China

   

2015-2017

Research Assistant, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China

2013-2015

Postdoctoral Fellow, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China

 

Awards and Honors

  • Peking University Excellent Advisor for Undergraduate Thesis (2024)
  • Peking University Medicine Youth Science and Technology Award (2023)
  • Asian Core Program Lectureship Award (2023)
  • Yangtze River Scholar Award Program for Young Scholars(2022)
  • Rising Stars from the Beijing Nova Program (2020)
  • Luye Biomedical Outstanding Young Scholar Award (2020)
  • ExcellentPostdoctoral Fellow of Peking University (2015)
  • Tianjin Excellent Doctoral Thesis (2014)

 

Research Interests

1. Methodologies on halogenation reactions

2. Methodologies on aromatic functionalization

 

Grant Funding

Grant period

Grant Type

Funding Agency

Amount

(million RMB)

2019-2022

National Key Research and

Development Program

(2019YFC1708902), co-PI

Ministry of

Science and

Technology

0.92

2023-2026

National Key Research and

Development Program

(2023YFF1205103), co-PI

0.68

2024-2027

General Program of National

Natural Science Fund

(22371007), PI

National Natural Science

Foundation of China

0.5

2021-2024

General Program of National

Natural Science Fund

(22071005), PI

0.63

2019-2022

General Program of National Natural Science Fund

(21871011), PI

0.65

2017-2019

Youth Program of National Natural Science Fund

(21602005), PI

0.21

2018-2023

Start-up Fund, PI

Peking University

1.00

2022-2026

Yangtze River Scholar Award Program for Young Scholars

1.00

2020-2022

Beijing Nova ProgramZ201100006820099

Natural Science Foundation of Beijing

0.55

2022-2024

Beijing Nova Program

Z211100002121163

0.15

 

Publications

  • Tieqiao Wang, Chao Li, Jingxuan Mi, Hongye Wang, Lei Chen, Qingxuan Kong1 Ning Jiao, Song Song,* Skeletal Editing of Pyridine and Quinoline N-Oxides through Nitrogen to Carbon Single Atom Swap.CCS Chem.2024, DOI: 10.31635/ccschem.024.202404133
  • Chao Li, Zixi Yan, Bingding Wang, Jiaxing Li, WeipingLyu, Zhixing Wang, Ning Jiao*, Song Song*, Regioselective synthesis of 4-functionalized pyridines. Chem2024, 10, 628.
  • Chao Li, Lei Chen, Hongye Wang, Zixi Yan, Bin Lyu, WeipingLyu, Changwei Jiang, Dehua Lu, Jiaxing Li, Ning Jiao, Song Song*, C—F Bond Insertion into Indoles with CHBr2F: An Efficient Method to Synthesize Fluorinated Quinolines and Quinolones. Chin. J. Chem.2024, 42, 1128.
  • Hongye Wang, Zhaoting Li, Rongheng Dai, Ning Jiao, Song Song*, An efficient and mild oxidative approach from thiols to sulfonyl derivatives with DMSO/HBr. Chem. Sci.2023, 14, 13228.
  • Weijin Wang, Hongye Wang, Rongheng Dai, Yachong Wang, Zhaoting Li, Xiaoxue Yang, Bin Lu, Ning Jiao, Song Song*, Organocatalytic Deoxyhalogenation of Alcohols with Inorganic Halides. ACS Catal. 2023, 13, 9033.
  • Hongliang Zhang, Weijin Wang, Bingding Wang, Hui Tan, Ning Jiao, Song Song*, Electrophilic amidomethylation of areneswithDMSO/MeCN reagents. Org. Chem. Front.2023, 9, 2430.
  • Weijin Wang, Xiaoxue Yang, Rongheng Dai, Zixi Yan, Jialiang Wei, Xiaodong Dou, Xu Qiu, Hongliang Zhang, Chen Wang, Yameng Liu,Song Song*, Ning Jiao*, Catalytic Electrophilic Halogenation of Arenes with Electron-Withdrawing Substituents. J. Am. Chem. Soc.2022, 144, 13415.
  • Xinwei Li, Zengrui Cheng, Jianzhong Liu, Ziyao Zhang, Song Song*, Ning Jiao*, Selective desaturation of amides: a direct approach to enamides. Chem. Sci.2022, 13, 9056.
  • Weijin Wang, Xinyao Li, Xiaoxue Yang, Lingsheng Ai, Zhiwen Gong, Ning Jiao, Song Song*, Oxoammonium salts are catalysing efficient and selective halogenation of olefins, alkynes and aromatics. Nat. Commun.2021, 12, 3873.
  • Hao Wu, Xinyao Li, Zixi Yan, Nana Ma, Song Song*, Guisheng, Zhang*, Ning Jiao*, Cu(I)-Catalyzed [2 + 2 + 1] Cycloaddition of Amines, Alkynes, and Ketenes: An Umpolung and Regioselective Approach to Full-Substituted β-Pyrrolinones. Org. Lett. 2021, 23, 762.
  • Song Song,Xinyao Li, Jialiang Wei, Weijin Wang, Yiqun Zhang, Lingsheng Ai, Yuchao Zhu, Xiaomeng Shi, Xiaohui Zhang, Ning Jiao*, DMSO-catalysed late-stage chlorination of (hetero)arenes. Nat. Catal. 2020, 3, 107.
  • Xiaojin Wen, Xinyao Li, Xiao Luo, Weijin Wang, Song Song*, Ning Jiao*, Intramolecular Csp3-H/C-C bond amination of alkyl azides for the selective synthesis of cyclic imines and tertiary amines. Chem. Sci.2020,11, 4482.
  • Weijin Wang, TongyuHuo, Xinyi Zhao, Qixue Qin, Yujie Liang, Song Song*, Guosheng Liu, Ning Jiao*, Nitromethane-Enabled Fluorination of Styrenes and Arenes. CCS Chem.2020, 2, 566.
  • Qixue Qin, Weijin Wang, Cheng Zhang, Song Song*, Ning Jiao*, A metal-free desulfurizing radical reductive C–C coupling of thiols and alkenes.Chem. Commun. 2019, 55, 10583.
  • Xu Qiu, Xiaoxue Yang, Yiqun Zhang, Song Song*, Ning Jiao, Efficient and practical synthesis of unsymmetrical disulfides via base-catalyzed aerobic oxidative dehydrogenative coupling of thiols. Org. Chem. Front.2019, 6, 2220.
  • Jianzhong Liu, Xiaojin Wen, Chong Qin, Xinyao Li, Xiao Luo, Ao Sun, Bencong Zhu, Song Song*, Ning Jiao*, Oxygenation of Simple Olefins through Selective Allylic C-C BondCleavage: A Direct Approach to Cinnamyl Aldehydes. Angew. Chem. Int. Ed. 2017, 56, 11940.
  • Song Song*,Yiqun Zhang, AdeliYeerlan, Bencong Zhu, Jianzhong Liu, Ning Jiao*, Cs2CO3-Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes.Angew. Chem. Int. Ed. 2017, 56, 2487.
  • Yuchao Zhu, Xiaojin Wen, Song Song*, Ning Jiao*, Silver-Catalyzed Radical Transformation of Aliphatic Carboxylic Acids to Oxime Ethers. ACS Catal.2016, 6, 6465.
  • Zhu Yuchao, Li Xinyao, Wang Xiaoyang, Huang Xiaoqiang, Shen Tao, Zhang Yiqun, Sun Xiang, Zou Miancheng, Song Song*, Ning Jiao*, Silver-Catalyzed Decarboxylative Azidation of Aliphatic Carboxylic Acids. Org. Lett. 2015, 17, 4702.
  • Song Song,Xiang Sun, Yizhi Yuan, Ning Jiao*, Efficient and practical oxidative bromination and iodination of arenes and heteroarenes with DMSO and hydrogen halide: A mild protocol for late-stage functionalization.Org. Lett. 2015, 17, 2886.
  • Song Song,Xinwei Li, Xiang Sun, Yizhi Yuan, Ning Jiao*, Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid. Green Chem.2015, 17, 3285.
  • Song Song,Xiaoqiang Huang, Yu-Feng Liang, Conghui Tang, Xinwei Li, Ning Jiao*, From simple organobromides or olefins to highly value-added bromohydrins: a versatile performance of dimethyl sulfoxide. Green Chem. 2015, 17, 2727.

 

Prior to PKU

  • Song Song, Shou-Fei Zhu, Shuang Yang, Shen Li, Qi-Lin Zhou*, Enantioselective iridium-catalyzed hydrogenation of β,γ-unsaturated carboxylic acids: An efficient approach to chiral 4-alkyl-4-aryl butanoic acids. Angew. Chem. Int. Ed. 2012, 51, 2708.
  • Song Song, Shou-Fei Zhu, Yan-Bo Yu, Qi-Lin Zhou*, Carboxy-directed asymmetric hydrogenation of 1,1-diarylethenes and 1,1-dialkylethenes. Angew. Chem. Int. Ed. 2013, 52, 1556.
  • Song Song, Shou-Fei Zhu, Liu-Yang Pu, Qi-Lin Zhou*, Iridium-catalyzed enantioselective hydrogenation of unsaturated heterocyclic acids. Angew. Chem. Int. Ed. 2013, 52, 6072.
  • Song Song, Shou-Fei Zhu, Shen Li, Qi-Lin Zhou*, Iridium-Catalyzed Enantioselective Hydrogenation of α,β-Unsaturated Carboxylic Acids with Tetrasubstituted Olefins.Org. Lett. 2013, 14, 3722.

 

Patents

  1. Song Song, Ning Jiao, Weijin Wang. Rongheng Dai. An efficient halogenation synthesis method for alkyl halides. Patent No. ZL202210308725.1
  2. Song Song, Ning Jiao, Rongheng Dai. An efficient synthesis method for aryl alkyl thioethers. Patent No.ZL202210444692.3
  3. Ning Jiao, Song Song. Low-cost and efficient synthesis of halogenated alcohols and their derivatives. Patent No. ZL201510033063.1
  4. Ning Jiao, Yufeng Liang, Song Song. An efficient synthesis method for catechol compounds.Patent No. ZL201610166390.9
  5. Ning Jiao, Song Song, Weijin Wang.An efficient synthesis method for aryl halides.Patent No. ZL202011069035.2
  6. Ning Jiao, Siwang Yu, Song Song, Yameng Liu, Simin Yang. Phenoxy carboxylic acid compounds and medical uses thereof. Patent No. ZL201910783280.0
  7. Ning Jiao,Song Song, Shenan Wang, Jialiang Wei. A synthesis method of fipronil and its analogues. Patent No. ZL 201910510802X
  8. Yimin Cui, Xiaocong Pang, Yanlun Gu, Xiaojiao Sun, Bingqi Dong, Song Song, Haitao Liu, Xu He. Indazole hydrazide compound and application thereof. Patent No. WO 2022/170822

 

Invited Lectures

  1. Chiral China 2024 Symposium (2024/7), Kunming
  2. The 2nd Slender West Lake Synthetic Chemistry Forum (2024/5), Yangzhou
  3. The 16th International Conference on Cutting-Edge Chemistry in Asia (2023/12), Singapore
  4. The Chinese National Conference on Synthetic Chemistry (2023/10), Guangzhou
  5. Seminar on Frontiers of Synthetic Chemistry (2020/12), Beijing

 

Mentoring

Time

Name

Prev. Position

Current Position

2023-present

Qingxuan Kong

PhD student

 

2022-present

Changwei Jiang

PhD student

 

2022-present

Wenshu Hu

PhD student

 

2021-present

Lei Chen

PhD student

 

2021-present

Bin Lu

PhD student

 

2020-present

Chao Li

PhD student

 

2018-2022

Hongliang Zhang

PhD student

Betta Pharmaceuticals Co., Ltd.

2023-present

Tieqiao Wang

Master student

 

2023-present

Jingxuan Mi

Master student

 

2022-present

Zhaoting Li

Master student

 

2022-present

Jiaxing Li

Master student

 

2021-2024

Shihan Geng

Master student

PhD student at Peking University

2021-2024

Hongye Wang

Master student

PhD student at Brown University

2020-2023

Bingding Wang

Master student

Dynamics Inc. Co.,Ltd.

2019-2022

LingyuSu

Master student

PhD student at Peking University

2019-2022

Rongheng Dai

Master student

Yunnan Baiyao Group Co., Ltd.

2018-2021

Zixi Yan

Master student

PhD student at Emory University

2023-present

Haoming Qin

Bachelor student

 

2021-2023

Weijin Wang

Bachelor student

PhD student atécole Polytechnique Fédérale de Lausanne

 

Teaching

Organic Chemistry (Department of MedicinalChemitry)

2019-present (~40 undergraduate students), ~36 hours/year

Organic Chemistry (Department of Language and Culture in Medicine)

2019-present (~40 undergraduate students), ~18 hours/year

Organic Chemistry Labs

2019-present (~120 undergraduate students), ~40 hours/year

 

Service

  • Member of the Chinese Chemical Society(2015-present)
  • Member of the Chinese Pharmaceutical Association (2023-present)
  • Assoc. Director of the Medicinal Chemistry Department(2023-present)
  • Reviewers for Research Journals(2015-present)
  • Grant Reviewer for National Natural Science Foundation of China (2018-present)