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JIA Yanxing

Professor

Professor

Research Areas

Organic Chemistry

Medicinal Chemistry

 

Education & Positions

Lanzhou University, B.S., 1997 Lanzhou University, Ph.D., 2002 Centre National de la Recherche Scientifique (CNRS), Institut de Chimie des Substances Naturelles (ICSN), France, Postdoctoral Fellow, 2002-2007 Peking University, Associate Professor 2007-2011, Professor 2011-

 

Faculty Accolades

Asian Core Program Lectureship Award (Hongkong, Japan) 2013

Distinguished Young Scholar Award for bio-pharmaceuticalfrom Peking University and Luye Pharma 2012

CAPA (Chinese-American Chemistry & Chemical Biology Professors Association) Distinguished Faculty Award 2011

Asian Core Program Lectureship Award (Thailand) 2010

“Program for New Century Excellent Talents in University”, Ministry of Education of China 2009

Research Interests:

1.    Natural products total synthesis;

2.    Medicinal chemistry;

3.    Development of new synthetic methods.

 

Grants and fundings

National Natural Science Founation of China (NSFC)

National Major Scientific and Technological Special Project for “Significant New Drugs Development”

 

Publications

1.  Li, L.; Chen, Z.; Zhang, X.; Jia, Y.* Divergent Strategy in Natural Product Total Synthesis. Chem. Rev. 2018, 118, 3752–3832.

2.  Liu, H.; Jia, Y.* Ergot alkaloids: synthetic approaches to lysergic acid and clavine alkaloids. Nat. Prod. Rep. 2017, 34, 411–432.

3.  Lv, J.; Wang, B.; Yuan, K.; Wang, Y.; Jia, Y.* Regioselective Direct C-4 Functionalization of Indole: Total Syntheses of (–)-Agroclavine and (–)-Elymoclavine. Org. Lett. 2017, 19, 3664–3667.

4.  Liu, H.;  Zhang, X.; Shan, D.; Pitchakuntla, M.; Ma, Y.; Jia, Y.* Total Syntheses of Festuclavine, Pyroclavine, Costaclavine, epi-Costaclavine, Pibocin A, 9-Deacetoxyfumigaclavine C, Fumigaclavine G, and Dihydrosetoclavine. Org. Lett. 2017, 19, 3323–3326.

5.  Li, L.; Aibibula, P.; Jia, Q.; Jia, Y.* Total Syntheses of Naucleamides A?C and E, Geissoschizine, Geissoschizol, (E)?Isositsirikine, and 16-epi-(E)?Isositsirikine. Org. Lett. 2017, 19, 2642–2645.

6.  Huang, B.; Zhang, F.; Song, Y.; Wang, X.; Wang, M.; Gong, Z.; Su, R.; Yu, G.; Jia, Y.* Gram Scale Syntheses of (-)-Incarvillateine and Its Analogs. Discovery of Potent Analgesics for Neuropathic Pain. J. Med. Chem. 2016, 59, 3953–3963.

7.  Huang, B.; Guo, L.; Jia, Y.* Protecting-Group-Free Enantioselective Synthesis of (-)-Pallavicinin and (+)-Neopallavicinin. Angew. Chem. Int. Ed. 2015, 54, 13599–13603.

8.  Li, L.; Yang, Q.; Wang, Y.; Jia, Y.* Catalytic Asymmetric Total Synthesis of (-)-Galanthamine and (-)-Lycoramine. Angew. Chem. Int. Ed. 2015, 54, 6255–6259.

9.  Shan, D.; Gao, Y.; Jia, Y.* Intramolecular Larock Indole Synthesis: Preparation of 3,4-Fused Tricyclic Indoles and Total Synthesis of Fargesine. Angew. Chem. Int. Ed. 2013, 52, 4902–4905.

10. Qin, H.; Xu, Z.; Cui, Y.; Jia, Y.* Total Synthesis of (±)-Decursivine and (±)-Serotobenine: A Witkop Photocyclization/Elimination/O-Michael Addition Cascade Approach. Angew. Chem. Int. Ed. 2011, 50, 4447–4449. 

 

More: http://sklnbd.bjmu.edu.cn/team/jiayanxing/